Posted on

LMU 242 – Boosting Immunity with Turkey Tail Mushroom: A Key to Breast Cancer Recovery

LMU-242

Boosting Immunity with Turkey Tail Mushroom: A Key to Breast Cancer Recovery

Source: Journal Oncology (2012)

Lifestyle Medicine Update (May 11, 2022)

Introduction:

Medicinal mushrooms, including Turkey Tail, have garnered attention for their immune-boosting properties. A study in Oncology (May 2012) unveils how Turkey Tail can enhance the immune system in breast cancer patients after conventional treatments. Its roots in Asian medicine and immunological activity suggest broader applications for immune support, particularly among the aging population. Explore the remarkable impact of medicinal mushrooms on well-being.

Unveiling the Power of Medicinal Mushrooms

Over the years, there has been a remarkable body of research highlighting the potential of certain medicinal mushrooms to fortify the body’s immune system. Among these remarkable fungi are reishi, shiitake, maitake, cordyceps, and the intriguing Tramates Versicolor, commonly known as Turkey Tail. In our journey to understand the profound impact of these mushrooms, we stumble upon an eye-opening study published in the journal Oncology in May 2012—a study that sheds light on how Turkey Tail supplementation can significantly enhance the immune system in breast cancer patients, even after enduring surgery, radiation treatment, and, in some cases, chemotherapy.

Revitalizing the Immune System: A Glimpse into the Study

The study we’re discussing here is not just a standalone revelation. It is an extension of prior preclinical animal investigations and early human clinical data. This body of research converges on a promising hypothesis: the constituents found in Turkey Tail mushrooms may hold the key to improving outcomes in both estrogen receptor-negative and estrogen receptor-positive breast cancers. How? By counteracting the immunologic depressive effects of conventional treatments and bolstering disease-free survival through enhanced immunological surveillance and overcoming tumor antigen tolerance.

A Historical Perspective: Turkey Tail in Traditional Asian Medicine

Turkey Tail has a rich history in traditional Asian medicine, where it has been employed for its potential health benefits for centuries. Studies have spotlighted two vital proteoglycan fractions present in Turkey Tail: polysaccharide-K (PSK) and Polysaccharide-peptide (PSP). Both of these fractions exhibit notable anticancer properties.

Japan’s Prescription: PSK in Cancer Treatment

In Japan, PSK is routinely prescribed to cancer patients, offering support during and after radiation and chemotherapy treatments. Similarly, many naturopathic physicians (NDs) and integrative oncologists (MDs) in the United States have embraced the practice of recommending Turkey Tail supplements to breast cancer patients. The driving force behind its remarkable antitumor effects and impact on survival rates is believed to be its profound immunologic activity. Turkey Tail supplementation has shown the capacity to enhance both innate and adaptive immune responses.

The Optimal Dosage: 6 or 9 Grams of Turkey Tail

The 2012 study featured in Oncology administered Turkey Tail at varying dosages—3, 6, or 9 grams per day, depending on the patient’s condition. Notably, the most favorable outcomes were observed in patients receiving 6 or 9 grams of Turkey Tail daily, equivalent to approximately 1-2 teaspoons of Turkey Tail ground powder.

A Message for the Aging Population

While the focus of this study is on breast cancer patients, the broader implications are clear. Everyone, especially those aged 50 and beyond, should contemplate incorporating medicinal mushrooms into their health regimen. This proactive step may help stave off the typical age-related decline in immune system function that often occurs later in life. Various supplements containing medicinal mushrooms like reishi, maitake, shiitake, cordyceps, and, of course, Turkey Tail are readily available. The studies we’ve highlighted today suggest that breast cancer survivors, in particular, may benefit from supplements that provide a substantial dose of Turkey Tail mushroom to fortify their immune defences.

As we navigate the intricate world of health and wellness, it’s evident that nature’s wonders, like Turkey Tail mushroom, hold the potential to transform our lives positively. In the pursuit of robust immunity and enhanced well-being, these remarkable fungi stand as allies, supporting us every step of the way.

Reference:

Torkelson C.J., et al. Phase I clinical trial of tramates versicolor in women with breast cancer. Oncology. 2012: 251632. [Read the full study here](https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3369477/)

 

Eat Smart, Live Well, Look Great,

Dr. Meschino

Dr. James Meschino

Dr. James Meschino

ABOUT THE AUTHOR

Dr. James Meschino, DC, MS, ROHP, is an educator, author, and researcher having lectured to thousands of healthcare professionals across North America. He holds a Master’s Degree in Science with specialties in human nutrition and biology and is recognized as an expert in the field of nutrition, anti-aging, fitness, and wellness as well as the author of numerous books.

Posted on

LMU 154 – The Milky Way to Breast Health: Rethinking Dairy Consumption

LMU-154

LMU 154 – The Milky Way to Breast Health: Rethinking Dairy Consumption

Source: International Journal of Epidemiology (2020)

Lifestyle Medicine Update (Mar 1, 2020)

Introduction:

The dietary landscape is ever-evolving, and it’s often challenging to separate fact from fiction, especially when it comes to our health. For years, dairy milk has held a prime spot in the Western diet, touted for its calcium content and nutritional benefits. However, a groundbreaking study from Loma Linda University, published in the International Journal of Epidemiology in February 2020, has shaken the foundations of this age-old belief. This research has brought to light a startling revelation: dairy milk consumption may be linked to an increased risk of breast cancer in women, with the risk escalating by as much as 80%, depending on the quantity consumed.

The Study: Unveiling the Dairy-Breast Cancer Connection

This extensive study delved into the dietary habits of nearly 53,000 North American women, all initially free of cancer, over an eight-year period. The research considered an array of factors, including demographics, family history of breast cancer, physical activity, alcohol consumption, medication use, breast cancer screening, and reproductive and gynecological history. By the end of the study, a total of 1,057 new breast cancer cases had emerged, casting a spotlight on the potential role of dairy milk in this concerning statistic.

Dairy Milk and the Breast Cancer Risk

The study’s findings painted a concerning picture. Those who regularly consumed dairy milk faced a significantly higher risk of breast cancer. Even as little as a quarter to a third of a cup of dairy milk per day was associated with a 30% increased risk of breast cancer. For those who indulged in up to one cup daily, the risk surged to 50%, and for those drinking two to three cups daily, the risk soared to a staggering 70% to 80%. Intriguingly, the type of milk—be it high-fat, low-fat, or non-fat—did not alter this disconcerting pattern. However, yogurt and cheese consumption appeared to have no discernible impact on breast cancer risk.

Embracing Dairy Alternatives: A Safer Choice?

In light of these findings, it’s worth considering alternatives to dairy milk. The study posits that dairy-alternate milk, such as soymilk, almond milk, or oat milk, could offer a safer choice for those concerned about breast cancer risk. Intriguingly, this aligns with the growing body of evidence that suggests vegans, who eschew dairy products entirely, may experience lower rates of breast cancer than non-vegetarians.

The IGF-1 Connection: Unravelling the Mystery

But what exactly is it about dairy milk that might contribute to breast cancer? One compelling theory centers around insulin-like growth factor-1 (IGF-1), a hormone that plays a crucial role in promoting certain cancers. Animals often receive growth hormone treatment to boost milk production, resulting in elevated IGF-1 levels in their blood. When humans consume milk or meat from these animals, they also ingest this hormone, potentially acting as a catalyst for cellular division and genetic mutations, ultimately increasing the risk of breast cancer.

A Changing Landscape: The Future of Dairy Farming and Consumption

These findings pose profound implications for dairy farming practices and dietary recommendations. As research mounts, the use of growth hormones in dairy farming and the public’s perception of milk consumption may undergo transformation. In this changing landscape, low-fat Greek yogurt emerges as a compelling dairy option, and dairy-alternate milks like soymilk, almond milk, or oat milk could become preferred choices, especially for those concerned about breast cancer risk.

Conclusion: Navigating the Dairy Dilemma

The journey into the world of dairy and its potential link to breast cancer is both enlightening and cautionary. As we continue to unravel the complexities of our diets and their impact on our health, it’s essential to approach such findings with an open mind. While more research is needed to solidify these connections, the evidence thus far invites us to explore dairy alternatives and consider a diversified approach to our nutritional choices.

References:

  1. Main Reference: Synnove Knutsen, Rawiwan Sirirat, Andrew Mashchak, Michael Orlich, Karen Jaceldo-Siegl, Gary E Fraser. Dairy, soy, and risk of breast cancer: those confounded milk. International Journal of Epidemiology, 2020. [Read the full study here](https://academic.oup.com/ije/advance-article-abstract/doi/10.1093/ije/dyaa007/5743492?redirectedFrom=fulltext).
  2.  [ScienceDaily – Dairy milk consumption may increase breast cancer risk](https://www.sciencedaily.com/releases/2020/02/200225101323.htm).
  3.  [Global News – Canadian dairy farmers will no longer use growth hormones under new USMCA deal](https://globalnews.ca/news/4533226/canadians-growth-hormones-dairy-usmca/)
 
Eat Smart. Live Well, Look Great
 

Dr. Meschino

Dr. James Meschino

Dr. James Meschino

ABOUT THE AUTHOR

Dr. James Meschino, DC, MS, ROHP, is an educator, author, and researcher having lectured to thousands of healthcare professionals across North America. He holds a Master’s Degree in Science with specialties in human nutrition and biology and is recognized as an expert in the field of nutrition, anti-aging, fitness, and wellness as well as the author of numerous books.

Posted on

LMU 97 – Nature’s Armor: A Bounty of Fruits and Vegetables in the Fight Against Breast Cancer

LMU-97

LMU 97 – Nature's Armor: A Bounty of Fruits and Vegetables in the Fight Against Breast Cancer

Source: International Journal of Cancer (July 2018)

Lifestyle Medicine Update (July 27, 2018)

Introduction

In the relentless quest to combat breast cancer, a landmark study emerged in July 2018, illuminating the remarkable armor that nature’s offerings provide. While previous investigations hinted at the link between fruit and vegetable consumption and reduced breast cancer risk, limitations loomed over their conclusions. Enter the pivotal study led by Maryam Farvid, et al., gracing the pages of the International Journal of Cancer. This groundbreaking research offers an unparalleled panorama of the pivotal role that a diet rich in fruits and vegetables plays in the arena of breast cancer prevention.

A Culmination of Insights: The Power of Abundant Produce

As the pages of the International Journal of Cancer unfurled, the contours of a comprehensive study came into view. Driven by a thirst for knowledge, the researchers delved into data culled from the Nurses’ Health Study (NHS, 1980-2012) and NHSII (1991-2013). Over 182,000 women, aged 27-59 at the study’s inception, embarked on a journey of dietary disclosure every four years, weaving a tapestry of nutritional insights. Yet, this journey ventured beyond diet, encompassing the labyrinth of breast cancer risk factors—from age and weight to smoking status and familial cancer history. A symphony of variables converged to unravel a profound truth—one that would redefine the canvas of breast cancer prevention.

The Nourishing Shield: Fruits and Vegetables Unveiled

As the data danced in the hands of researchers, the symphony of fruits and vegetables assumed center stage. The findings transcended mere consumption, revealing a staggering reality. Women who embraced a diet crowned by more than 5.5 servings of these nutritional gems daily wielded an 11% lower risk of breast cancer compared to their counterparts who embraced 2.5 or fewer servings. Each serving, whether a cup of raw leafy vegetables or half a cup of succulent fruits, wove a thread of protection against the ominous spectre of breast cancer. Yet, certain protagonists emerged from this nutritional ensemble—cruciferous vegetables, radiant in their green glory, and the sun-kissed brilliance of yellow and orange vegetables. Their embrace showcased a formidable association with reduced breast cancer risk, charting a path toward wellness.

A Multifaceted Arsenal: Fruits, Vegetables, and Aggressive Tumors

Unravelling the secrets within fruits and vegetables, the study ventured into the realm of tumor aggression. Here, the narrative took an unexpected turn. The warriors of health not only lowered breast cancer risk but also thwarted the ascent of more aggressive adversaries—ER-negative, HER2-positive, and basal-like tumors. This revelation etched the narrative of fruits and vegetables as custodians of health, fending off not only the conventional foe but also its fiercer incarnations.

Beyond Fiber: Unveiling the Nutrient Ensemble

In the theater of health, the spotlight often fixated on fiber as a guardian against breast cancer risk. However, this journey yielded a surprising twist—fruits and vegetables wielded their magic independently of their fiber content. Within their vibrant embrace, antioxidants, phytonutrients, and micronutrients wove an intricate tapestry of protection. This symphony of constituents stood as potent agents in the battle against breast cancer, casting light upon the path of prevention.

Guiding Lights: Lifestyle Factors and Beyond

As the study’s revelations echoed, they harmonized with other voices advocating for wellness. Beyond the world of fruits and vegetables, a chorus of lifestyle factors emerged as guiding lights in the symphony of prevention. An ideal weight, an alliance with regular exercise, a diet forsaking saturated fats, trans-fats, deep-fried fare, and alcohol, along with the maintenance of optimal vitamin D levels, painted a roadmap toward breast cancer resilience. The canvas of health embraced myriad hues, with each brushstroke imbued with the power to rewrite destinies.

A Call to Nourishment: A Tale of Transformation

The study’s narrative serves as a clarion call—a plea for transformation through nourishment. As individuals, we hold the palette of our health, capable of painting resilience against the canvas of life’s challenges. The fruits and vegetables that grace our tables extend an invitation—a dance of flavors that holds the promise of shielding against breast cancer’s incursions.

Conclusion: The Symphony of Wellness

In the grand symphony of health, the harmonious melodies of fruits and vegetables resound with remarkable potency. The research of Maryam Farvid and her team has cast a spotlight on a nutritional duo that transcends taste, serving as sentinels against breast cancer’s shadows. As we journey through life’s landscapes, the fruits and vegetables we embrace bear the promise of guarding our well-being—a testament to the power of nature’s offerings.

References

  1. Maryam S. Farvid et al. (2018). Fruit and vegetable consumption and breast cancer incidence: Repeated measures over 30 years of follow-up. International Journal of Cancer. [Link] (https://onlinelibrary.wiley.com/doi/abs/10.1002/ijc.31653)

Eat Smart, Live Well, Look Great

Dr. Meschino

Dr. James Meschino

Dr. James Meschino

ABOUT THE AUTHOR

Dr. James Meschino, DC, MS, ROHP, is an educator, author, and researcher having lectured to thousands of healthcare professionals across North America. He holds a Master’s Degree in Science with specialties in human nutrition and biology and is recognized as an expert in the field of nutrition, anti-aging, fitness, and wellness as well as the author of numerous books.

Posted on

LMU 44 – Enhancing Breast Cancer Outcomes: The Impact of Nutrition and Lifestyle Practices

Nutrition and Lifestyle Practices Shown to Reduce Breast Cancer

LMU 44 – Enhancing Breast Cancer Outcomes: The Impact of Nutrition and Lifestyle Practices

Source: Candian Medical Association Journal (February 21, 2017)

Lifestyle Medicine Update (March 1, 2017)

Introduction

In the realm of medical advancements, the role of nutrition and lifestyle modifications in improving breast cancer outcomes has gained substantial attention. A study published in the Canadian Medical Association Journal on February 21, 2017, delves into the impact of lifestyle changes on breast cancer recurrence, metastasis, and overall survival rates. This article sheds light on the compelling findings of this research, highlighting the crucial link between nutrition, lifestyle practices, and breast cancer outcomes.

Empowering Insights

The research review embarked on a critical inquiry: Can lifestyle modifications influence the recurrence of breast cancer and the survival rates of treated women? The outcomes of this investigation offer encouraging insights that align closely with the principles advocated within the Meschino Wellness Program.

Context and Motivation

While more than 90% of breast cancer patients are diagnosed with early-stage disease, an alarming 25% eventually succumb to distant metastasis. This staggering statistic underscores the urgency of exploring measures that could prevent recurrence and metastasis. Patients, driven by the desire to actively contribute to their well-being, seek strategies that encompass nutrition and lifestyle interventions.

Key Findings

The research brings to light several pivotal observations that underscore the substantial impact of lifestyle modifications on breast cancer outcomes:

  1. Weight Management: Weight gain during or post-breast cancer treatment is significantly linked to a higher risk of breast cancer-related mortality. Moreover, individuals who are overweight or obese at diagnosis experience poorer prognoses. This correlation is attributed to the elevation of insulin, insulin-like growth factors, estrogen levels, and pro-inflammatory cytokines associated with excess weight, which exacerbate breast cancer cell proliferation. Maintaining an ideal weight is, therefore, of paramount importance.
  2. Physical Activity: Physical activity emerges as a potent factor in reducing breast cancer recurrence. The effects of exercise on hormone levels, inflammation reduction, and insulin resistance reversal contribute to its robust impact. The Canadian Cancer Society and the American Cancer Society endorse a regimen of at least 30 minutes of moderate-intensity physical activity for at least five days a week, accompanied by two to three strength training sessions targeting major muscle groups.
  3. Dietary Choices: Observational studies indicate that high consumption of saturated fats and high-fat dairy products might be associated with increased breast cancer mortality. On the contrary, recent research suggests that soy products are safe for consumption, debunking concerns about their estrogen content. Although randomized trials are necessary to validate soy’s role in reducing breast cancer recurrence, existing evidence supports its inclusion in the diet.
  4. Smoking and Alcohol: Smoking among women with breast cancer elevates the risk of mortality. Similarly, alcohol consumption is linked to an increased risk of recurrence, particularly in estrogen-receptor-positive breast cancer cases.
  5. Supplements: Emerging data indicate the potential benefits of supplemental vitamin C intake in reducing breast cancer mortality. Vitamin D showcases advantages in maintaining a blood level within the range of 75–200 nmol/L.

Future Directions and Conclusions

While more clinical trials are warranted to validate the protective effects of certain lifestyle practices, the evidence underscores the substantial potential for improving breast cancer prognosis through dietary and lifestyle modifications. Adopting the strategies outlined in this research can significantly enhance long-term outcomes and overall health for breast cancer patients. Importantly, these practices are also relevant in the prevention of breast cancer development itself.

Reference

Hamer, J., and Warner, E., Lifestyle modifications for patients with breast cancer to improve prognosis and optimize overall health. CMAJ. February 21, 2017, vol. 189, no. 7.

http://www.cmaj.ca/content/189/7/E268

Dr. James Meschino

Dr. James Meschino

ABOUT THE AUTHOR

Dr. James Meschino, DC, MS, ROHP, is an educator, author, and researcher having lectured to thousands of healthcare professionals across North America. He holds a Master’s Degree in Science with specialties in human nutrition and biology and is recognized as an expert in the field of nutrition, anti-aging, fitness, and wellness as well as the author of numerous books.

Posted on

LMU – 07 Impact of Dietary Fat Intake on Breast Cancer Risk: Insights from the EPIC Study

LMU-07

LMU 07 - Impact of Dietary Fat Intake on Breast Cancer Risk: Insights from the EPIC Study

Source: Journal of the National Cancer Institute, April, 2014. Vol. 106, No.5

Lifestyle Medicine Update (April 22, 2016)

Introduction:

Welcome to Lifestyle Medicine Update, where we discuss the latest research on various health topics. In this edition, we delve into a study published in the Journal of the National Cancer Institute in April 2014, shedding light on the relationship between dietary fat intake and breast cancer risk. The study in question is part of the European Prospective Investigation into Cancer and Nutrition (EPIC), one of the most significant human cancer studies ever conducted. Let’s explore the findings and their implications for breast cancer prevention.

The EPIC Study: An Overview

The EPIC study has been ambitious, tracking 337,327 women across ten European countries for over 11.5 years. This extensive research aimed to identify potential links between diet, nutrition, and cancer, focusing on breast cancer. The study analyzed data from 10,062 breast cancer patients, making it a substantial and reliable source of information.

The Role of Dietary Fat

Researchers have long been interested in the role of dietary fat in breast cancer development. This study specifically examined the impact of total and saturated fat intake on breast cancer risk. The results highlighted a concerning connection between high-fat diets and increased breast cancer risk, particularly for women who consumed significant amounts of saturated fat.

Key Findings: Fat Intake and Breast Cancer Risk

The EPIC study revealed that women with the highest consumption of total fat and saturated fat had up to a 50% increased risk of breast cancer compared to those with the lowest intake of these fats. This finding suggests that dietary habits significantly affect breast cancer development.

Subclasses of Breast Cancer and Dietary Fat

Breast cancer is not a singular disease but comprises different subclasses based on receptor status. These include estrogen receptor-positive (ER+), estrogen receptor-negative (ER-), progesterone receptor-positive (PR+), progesterone receptor-negative (PR-), and Her-2 positive (Her-2+) or Her-2 negative (Her-2-).

The EPIC study provided insights into the association between dietary fat intake and specific subclasses of breast cancer. A high-fat diet, incredibly saturated fat, increases the risk of estrogen receptor-positive and progesterone receptor-positive breast cancer. Furthermore, saturated fat was mainly linked to aggressive Her-2-positive breast cancer development. Researchers theorized that saturated fat may contribute to over-expression of the Her-2 receptor, thereby increasing the risk of this form of breast cancer.

Genetics and Dietary Fat: Unraveling the Connection

Genetic inheritance only accounts for a small percentage (10-20%) of breast cancer cases. Therefore, the EPIC study’s findings on the substantial impact of dietary fat intake on breast cancer risk are essential. The results suggest that adopting healthier dietary habits may help reduce the risk of breast cancer, providing an actionable approach to prevention.

Recommendations for Breast Cancer Prevention

As a proactive measure to prevent breast cancer, it is crucial to encourage women to modify their diets and reduce their total fat and saturated fat intake. Foods typically high in unhealthy fats include beef, pork, high-fat dairy products, deep-fried foods, creamy salad dressings, breaded meats, and high-fat pastries. By replacing these items with healthier alternatives, individuals can reduce their risk of not only breast cancer but also heart disease and other cancers, as indicated by the EPIC and other research studies.

Conclusion

The EPIC study has offered valuable insights into the relationship between dietary fat intake and breast cancer risk. By identifying a 50% increased risk of breast cancer associated with high total fat and saturated fat consumption, the study emphasizes the importance of adopting healthier eating habits to mitigate this risk. By reducing the intake of saturated fats and choosing a balanced and nutritious diet, women can take proactive steps toward protecting their breast health.

We hope you will share this critical information with the women in your life. The EPIC study’s research reference is provided below for those interested in delving further into the topic.

Reference:

S. Sieri, P. Chiodini, C. Agnoli, V. Pala, F. Berrino, A. Trichopoulou, V. Benetou, E. Vasilopoulou, M.-J. Sanchez, M.-D. Chirlaque, P. Amiano, J. R. Quiros, E. Ardanaz, G. Buckland, G. Masala, S. Panico, S. Grioni, C. Sacerdote, R. Tumino, M.-C. Boutron-Ruault, F. Clavel-Chapelon, G. Fagherazzi, P. H. M. Peeters, C. H. van Gils, H. B. Bueno-de-Mesquita, H. J. van Kranen, T. J. Key, R. C. Travis, K. T. Khaw, N. J. Wareham, R. Kaaks, A. Lukanova, H. Boeing, M. Schutze, E. Sonestedt, E. Wirfalt, M. Sund, A. Andersson, V. Chajes, S. Rinaldi, I. Romieu, E. Weiderpass, G. Skeie, E. Dagrun, A. Tjonneland, J. Halkjaer, K. Overvard, M. A. Merritt, D. Cox, E. Riboli, V. Krogh. Dietary Fat Intake and Development of Specific Breast Cancer Subtypes. JNCI Journal of the National Cancer Institute, 2014. Vol 106, issue 5.
http://jnci.oxfordjournals.org/content/106/5/dju068

Dr. James Meschino

Dr. James Meschino

ABOUT THE AUTHOR

Dr. James Meschino, DC, MS, ROHP, is an educator, author, and researcher having lectured to thousands of healthcare professionals across North America. He holds a Master’s Degree in Science with specialties in human nutrition and biology and is recognized as an expert in the field of nutrition, anti-aging, fitness, and wellness as well as the author of numerous books.